Modafinil is a pain reliever used to treat drowsiness associated with narcolepsy (unexpected sleepiness and drowsiness). Modafinil is also approved by the United States Food and Drug Administration (FDA) for post sleep disorder (SWSD) and sleepiness associated with obstructive sleep apnea. However, the European Medicines Agency recommends limiting a new modafinil drug prescription to cases of narcotics due to the risk of neuropsychiatric, dermal and allergic side effects. At the same time, since these side effects are often observed in the first two weeks after taking the drug, its use is not limited by a previous prescription.


The off-label use of modafinil is also very popular as a relatively safe psychostimulant. Learn to be alert and active around the clock. This will help you succeed in many aspects of your life because you can do so much more than others. Do you think you have more opportunities and don’t trust your body’s whims? Get rid of restrictions and enjoy “inexplicable” achievements and amazing personal achievements!

Modafinil is needed when a life situation requires maximum focus and attention for more than a normal active day. It keeps you in a high energy state for a day or more, helps you control everything around you, and gives you great confidence that you can truly control the situation when others are exhausted.

Modafinil helps many people in situations where they need to be in the best shape and tone to use their full potential to achieve their goals. Help in sports training tired, can increase body endurance and reduce physical fatigue. In this regard, there has been an increase in the number of cases where athletes have been accused of using modafinil as a sports supplement in international competitions.

Мodafinil in sport

Мodafinil in sport

Modafinil is currently on the World Anti-Doping Agency’s list of drugs that athletes should not take, whether in preparation for competition, during the training process, and directly during tournaments. It is a powerful stimulant that improves memory, intellectual acuity and other parameters of mental activity. It effectively relieves fatigue and restores the cognitive functions of the brain.

Modafinil is one of the best remedies for boosting mental activity, reducing the need for sleep and depression. The absence of side effects such as addiction, over-motivation and a reduced sense of responsibility is a very important positive point.

For polyphasic sleep practitioners, in clear dream management, the use of Modafinil helps achieve a clear and controlled sleep schedule. This is due to the duration of the activity which is strictly controlled (depending on the dose).

Action mechanism

Action mechanism

Despite intensive research on the interaction of modafinil with a large number of neurotransmitters, the exact mechanism or all of the mechanisms of interaction remains unclear. Modafinil, like other stimulants, is likely to increase the release of monomers – particularly the catecholamines norepinephrine and dopamine – from synaptic clefts. However, modafinil increases histamine levels in the hypothalamus, leading some researchers to consider modafinil a “sleep drug” rather than a classic stimulant like amphetamine.

Studies show that modafinil has “low serious abuse potential” and “does not develop addiction in new users.” The combined effect of modafinil on the catecholamine and histamine pathways reduces the risk of abuse compared to traditional stimulants, while maintaining its effectiveness as a sleep aid.